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ADHD Medication and Heart Health: The Medication Linked with the Risk of Heart Disease

Amanda Green – Cardiology Department 

Link: doi:10.1001/jamapsychiatry.2023.4294 

Date Published: Jan. 2024



Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition that is marked by patterns of symptoms such as inattentiveness, impulsivity, and hyperactivity. Because ADHD medications (such as methylphenidate and amphetamine) are highly recommended to prevent these symptoms, the use of ADHD  has escalated with a 10% increase in 2021 than 2020, according to a health industry analytics firm IQVIA. However, recent studies have shown an increased risk of cardiovascular disease (CVD) linked with long-term use of such medications. A study by Zhang et al assesses the association between long-term usage of ADHD medication and the risk of cardiovascular diseases. Individuals who received their ADHD diagnosis/medication between 2007 and 2020 were studied. The outcome of this study concluded that long-term use of ADHD medications was associated with an increased risk of cardiovascular disease. More specifically, these individuals faced a higher risk of two specific conditions: hypertension and arterial disease. 


In summary, this article highlights the importance of weighing the possible risks of ADHD medication use. Therefore, carefully monitoring the cardiovascular signs of an individual who has taken ADHD medication long-term should be advised. While it’s acknowledged that ADHD medication can be beneficial, such as aiding in extended focus, improved listening, and reduced fidgeting for many individuals, other treatments such as therapy are viable, reducing risks for CVD associated with ADHD medication use. 


Bibliography: 

Zhang, L., Li, L., Andell, P., Garcia-Argibay, M., Quinn, P. D., D’Onofrio, B. M., Brikell, I., Kuja-Halkola, R., Lichtenstein, P., Johnell, K., Larsson, H., & Chang, Z. (2023). Attention-Deficit/Hyperactivity Disorder Medications and Long-Term Risk of Cardiovascular Diseases. JAMA Psychiatry

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